Reset with nutrients that target your inflammation at the root. - Yes, support my body's natural inflammatory response
GMP-Certified Manufacturing
Research-Driven Formulas
GPX - COOL DOWN
For Your Joints, Your Mobility, and Your Comfort.
Flexible and active.
Move without restriction
Maintains cartilage function & healthy inflammatory response
Support long-term joint health
Feel the Difference
Joint Discomfort Doesn't Have to Be a Limitation
Life Before
GPX - Cool Down
Life Before GPX - Cool Down
When everyday activities feel challenging
Supporting Joint Comfort Through Nutritional Ingredients
When ease of movement isn’t effortless
Life After
GPX - Cool Down
Life After GPX-Cool Down
Support for Joint Flexibility and Comfort
Nutritional support for joint function and long-term mobility
Support mobility to move freely, every day
Feel the Difference
Built for Joint Warriors
For those who:
Wake up to mornings feeling stiff
Struggle with ease of movement throughout the day
Looking for a natural way to support joint health and mobility?
Feel the Difference
The GPX - Cool Down Formula
Curcu-Quell
Support your body’s natural inflammatory response and promote everyday joint comfort and mobility — with turmeric and ginger working from the inside out.
ReMotion
Nutritional support for healthy cartilage joint comfort, flexibility, and daily movement — without compromise. Formulated to help you stay active, every day.
Mag-3x
Mag-3x delivers three high-absorption forms of magnesium to support relaxation, a balanced mood, and restful sleep — all through nervous system support.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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Why GPX - Cool Down
Practitioner-Formulated
Designed by clinical experts who understand real-world gut challenges.
100% Potency Guarantee
What's on the label is what's in the capsule—no compromises.
Hypoallergenic
Free from common allergens—gentle on sensitive systems.
Empty Bottle Guarantee
Try it risk-free. Don't love it? Get your money back.
Non-GMO
No genetically modified ingredients. Ever.
GMP-Certified Manufacturing
Made in facilities that meet strict Good Manufacturing Practices.
Research-Driven Formulas
Every ingredient is backed by science and clinical studies.
3rd-Party Tested
Independent testing ensures safety, purity, and performance.
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What’s Inside Your Daily Cool Down Pack
Morning Pack (A.M.)
1x Curcu-Quell
1x ReMotion
2x Mag-3x
Evening Pack (P.M.)
1x Curcu-Quell
1x ReMotion
2x Mag-3x
Feel the Difference
GPX - Cool Down
$109.35/ 3 months
$115.105% offQuantity
Move without restriction
Maintains cartilage function & healthy inflammatory response
Maintains cartilage function
Customer Reviews
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Clinically-Backed Ingredients for Real Results
GPX–Cool Down combines research-supported nutrients to support a healthy inflammatory response, joint comfort, and mobility. Each formula in the pack—Curcu-Quell, ReMotion, and Mag-3x—is crafted with ingredients studied for their role in maintaining joint function and flexibility over time.
Feel the Difference
Frequently Asked Questions
Ready to Move Freely Again?
Support joint and muscle comfort with nutrients that help maintain a healthy inflammatory response. With daily use, feel confident in every step.
Feel the Difference
2025 © Copyright Dr. Steven Geanopulos. All rights reserved.
Research & Scientific Proofs
Curcu-Quell
1. The Lancet, Volume 382, Issue 9894, Pages 769 - 779, 31 August 2013. doi:10.1016/S0140-6736(13)60900-9
2. Van Wuck, Kim et al. Medicine & Science in Sports & Exercise: Aggravation of Exercise-Induced Intestinal Injury by Ibuprofen in Athletes. December 2012 - Volume 44 - Issue 12 - p 2257–2262
3. WebMD. (2018). Pain Management-Side Effects of Pain Medicines. [online] Available at:1. Krasinski SD, Russell RM, Samloff IM, Jacob RA, Dallal GE, McGandy RB, Hartz SC. Fundic atrophic gastritis in an elderly population. Effect on hemoglobin and several serum nutritional indicators. J Am Geriatr Soc. 1986 Nov;34(11):800-6.
4. Shaheen N. J., Hansen R. A., Morgan D. R., et al. The burden of gastrointestinal and liver diseases, 2006. The American Journal of Gastroenterology. 2006;101(9):2128–2138.
5. Leri, F., Ayzenberg, M., Voyce, S. J., Klein, A., Hartz, L., & Smego Jr, R. A. (2013). Four-year trends of inappropriate proton pump inhibitor use after hospital discharge. Southern medical journal, 106(4), 270-273.
6. Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. [PMID: 15321791].
7. New York University Langone Medical Center. Betaine Hydrochloride. http://www.med.nyu.educontent? ChunkIID=21560. Last Reviewed 2011.
8. Taussig, SJ. The mechanism of the physiological action of bromelain. Medical Hypothesis 1980;6:99-104.[Accessed 23 Mar. 2018].
9. Kumar S, Ahuja V, Sankar MJ, Kumar A, Moss AC. Curcumin for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev 2012 Oct 17;10:CD008424.
10. Baliga MS, Joseph N, Venkataranganna MV, Saxena A,Ponemone V, Fayad R. Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations. Food Funct2012 Nov;3(11):1109-17.
11. Bengmark S, Mesa MD, Gil A. Plant-derived health:the effects of turmeric and curcuminoids. Nutr Hosp 2009 May-Jun;24(3):273-81.
12. Kapakos G, Youreva V, Srivastava AK. Cardiovascular protection by curcumin: molecular aspects. Indian J Biochem Biophys 2012 Oct;49(5):306-15.
13. Lopresti AL, Hood SD, Drummond PD. Multiple Antidepressant potential modes of action of curcumin:a review of its anti-inflammatory, monoaminergic,antioxidant, immune-modulating and neuroprotective effects. J Psychopharmacol 2012 Dec;26(12):1512-24.
14. Jellin JM, Gregor PJ, Batz F, Hitchens K et al. Pharmacist’s letter/ Prescriber’s letter Natural Medicines Comprehensive Database. 4th ed. Stockton, CA: Therapeutic Research Faculty; 2002: p.584-586.
15. Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med 2009;15:129-32.
16. Bliddal H, Rosetzsky A, Schlichting P, et al. A randomized, placebo-controlled crossover study of ginger extracts and ibuprofen in osteoarthritis. Osteoarthritis Cartilage 2000;8:9-12.
17. Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001;44:2531-8.
18. Sengupta, K., Alluri, K. V., Satish, A. R., Mishra, S., Golakoti, T., Sarma, K. V., ... & Raychaudhuri, S. P. (2008). A double blind, randomized, placebo controlled study of the efficacy and safety of 5-
19. Loxin® for treatment of osteoarthritis of the knee. Arthritis research & therapy, 10(4), R85.
20. Shoba₁, G., Joy₁, D., Joseph₁, T., Rajendran₂, M. M. R., & Srinivas₂, P. S. S. R. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.Planta medica,64, 353-356.
ReMotion
1. Murphy, Louise, and Charles G. Helmick. "The impact of osteoarthritis in the United States: a population-health perspective: A population-based review of the fourth most common cause of hospitalization in US adults." Orthopaedic Nursing 31.2 (2012): 85-91.
2. Usha, P. R., and M. U. R. Naidu. "Randomised, double-blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and their combination in osteoarthritis." Clinical drug investigation 24.6 (2004): 353-363.
Mag-3x
1. “Nutrient Intakes Percent of population 2 years old and over with adequate intakes based on average requirement”. Community Nutrition Mapping Project. 2009-07-29. Retrieved 2012-02-11.
2. Nielsen, F.H., Milne, D.B., Klevay, L.M., Gallagher, S., Johnson, L.K. 2007. Dietary magnesium deficiency induces heart rhythm changes, impairs glucose tolerance, and decreases serum cholesterol in post menopausal women. Journal of the American College of Nutrition. 26(2):121-132.
3. The Magnesium Miracle, by Carolyn Dean, M.D., N.D., Ballantine Books, 2007.
4. 1992: Seelig MS, Altura BT, Resnick LM, Handwerker SM, Altura BM: Low magnesium, a common denominator in pathologic processes in diabetes mellitus, cardiovascular disease, and eclampsia. J Am Coll Nutr 11:608.
5. G Moorkens, B Manuel y Keenoy, J Vertommen, S Meludu, M Noe, I De Leeuw. Magnesium defi cit in a sample of the Belgian population presenting with chronic fatigue. Magnes Res. 1997 Dec;10(4):329- 37. PMID: 9513929
6. J Eisinger, A Plantamura, P A Marie, T Ayavou. Selenium and magnesium status in fi bromyalgia. Magnes Res. 1994 Dec;7(3- 4):285-8. PMID: 77866927. 1995: Seelig MS: Prenatal and genetic magnesium defi ciency in cardiomyopathy; possible vitamin and trace mineral interactions. In “Pediatric Nutrition XXII”, Ed F Lifshitz, CRC Press, Boca Raton, FL, pp 197-224.
7. Martha Rodríguez-Morán, Fernando Guerrero-Romero. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized doubleblind controlled trial. Diabetes Care. 2003 Apr;26(4):1147-52. PMID: 12663588
8. F Facchinetti, P Borella, G Sances, L Fioroni, R E Nappi, A R Genazzani. Oral magnesium successfully relieves premenstrual mood changes. Obstet Gynecol. 1991 Aug;78(2):177-81. PMID: 20677599. 1995: Seelig MS: Calcium and magnesium deposits in disease, with emphasis on arteriosclerosis, in Ed. G Berthon “Handbook on Metal-Ligand Interactions in Biological Fluids” vol 2 (Part 4): Chapt 5, Dekker, N.Y., N.Y., pp 914-934.
9. Afshin Samaie, Nabiollah Asghari, Raheb Ghorbani, Jafar Arda. Blood Magnesium levels in migraineurs within and between the headache attacks: a case control study. Pan Afr Med J. 2012; 11:46. Epub 2012 Mar 15. PMID: 22593782
10. 1996: Seelig MS & Elin RJ: Is there a place for magnesium in the treatment of acute myocardial infarction? Am Heart J 132 (Part 2):471-477.
11. 1996: Antman EM, Seelig MS, Fleischmann K, Lau J, Kuntz K, Berkey CS, McIntosh M: Editorial. Magnesium in acute myocardial infarction: scientifi c, statistical, and economic rationale for its use. Cardiovasc Drugs & Therapy 10:297-301.
12. 1997: Seelig MS, Altura BM: Editorial. How best to determine magnesium requirement: need to consider cardiotherapeutic drugs that affect its retention. J Am Coll Nutr 16:2-4.
13. Zemel, P.C., Zemel, M.B., Urberg, M., Douglas, F.L., Geiser, R. & Sowers, J.R. (1990): Metabolic and hemodynamic effects of magnesium supplementation in patients with essential hypertension. Am. J. Clin. Nutr. 51, 665-669.
14. 1990: Seelig MS: Increased magnesium need with use of combined estrogen and calcium for osteoporosis treatment. Magnesium Res 3:197-215.
15. 1998: Seelig MS: Review and hypothesis: might patients with the chronic fatigue syndrome have latent tetany of magnesium defi ciency. J Chron Fatigue Syndr 4:77-108.
16. Clin Gastroenterol Hepatol. 2013 Dec 13. pii: S1542- 3565(13)01893-4. doi: 10.1016/j.cgh.2013.12.005 PMID: 24342746
17. Massachusetts Institute Of Technology. “MIT: Magnesium May Reverse Middle-age Memory Loss.” ScienceDaily. ScienceDaily, 27 December 2004.